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Allele : Nrxn2<tm6Sud> neurexin II; targeted mutation 6, Thomas C Sudhof

Primary Identifier  MGI:5911112 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nrxn2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Part of exon 23 was deleted, and the gene interrupted between alternative splice site #5 into the 3' UTR. This knocks out both the alpha and the beta isoforms of the gene. Northern blots demonstrated that mRNA for the beta isoform was undetectable in brain, whereas for the alpha isoform a faint band of lower than wild-type molecular weight was detected.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele