Primary Identifier | MGI:5911979 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pkn1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was disrupted with the insertion of an IRES-lacZ-neo cassette. Western blot analysis confirmed the absence of PKN1 expression in homozygous mutant embryo extracts with no compensatory changes in PKN2 or PKN3 expression. |