Primary Identifier | MGI:5909921 | Allele Type | Targeted |
Attribute String | Null/knockout, Recombinase | Gene | Sox14 |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The targeting vector was constructed by replacing the Sox14 coding sequence with a cassette consisting of a 5' splice substrate followed by the cre gene and a bovine growth hormone polyadenylation signal (bGHpA) followed by a Frt flanked neomycin gene cassette by homologouse recombination in ES cells. The PGKneo cassette was removed after crossing with the FLPeR mice. |