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Allele : Tg(Cacng5-cre)181Tjmc transgene insertion 181, Thomas J McHugh

Primary Identifier  MGI:6117425 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Cacng5-cre)181Tjmc
Strain of Origin  C57BL/6 Is Recombinase  true
Is Wild Type  false
molecularNote  The bacterial artificial chromosome (BAC) RP23-145G23 containing mouse calcium channel, voltagedependent, gamma subunit 5 (Cacng5) gene was modified to insert a Cre-FRT-Amp-FRT cassette at the start site of Cacng5 translation. The ampicillin (Amp) marker was deleted and the Cre-modified BAC's were confirmed, purified and injected into C57BL/6 fertilized pronuclei. Five founders (lines 160, 181, 190, 212, 225) were generated. The 181 Cacng5-Cre line was determined to express Cre selectively in the CA2 area of hippocampus using immunohistochemistry with the anti-Cre antibody, and used for analyses.
  • mutations:
  • Insertion
  • synonyms:
  • Cacng5-Cre,
  • Cacng5-Cre
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

5 Publication categories

Trail: Allele