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Allele : Sphk2<tm1Geno> sphingosine kinase 2; targeted mutation 1, Genoway

Primary Identifier  MGI:6095628 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sphk2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  Originally published in Pushparaj PN et al. "Sphingosine kinase1 is pivotal for Fc{epsilon}RI-mediated mast cell signaling and functional responses in vitro and in vivo" (J Immunol. 2012 Sep 15;189(6):3262) but later retracted (see retraction PMID: 22956763 for more detail). The retraction did not impact the generation of the alleles performed by Genoway.
molecularNote  A neomycin resistance cassette replaced exons 4 through 7.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele