| Primary Identifier | MGI:5927713 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Gpr153 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GTGTCCCTGTCCCTCTCACG, CATAGTCTGGGGCTACTGGG, GGGAACACTGAGTTGGCATA and CTAGAAGCCACATCCCTGAG, which resulted in a 1029 bp deletion beginning at Chromosome 4 positive strand position 152,279,522 bp and ending after 152,280,550 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000398729 (exon 3) and 599 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 119 and early truncation 1 amino acids later. |
