| Primary Identifier | MGI:6111357 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | App |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 2 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. Flp-mediated recombination removed the FRT-flanked neo cassette. Exon 3 was removed through cre-mediated recombination. Western blot analysis demonstrates the absence of protein. |
