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Publication : Tnni3k influences cardiomyocyte S-phase activity and proliferation.

First Author  Purdy AL Year  2023
Journal  J Mol Cell Cardiol Volume  183
Pages  22-26 PubMed ID  37597489
Mgi Jnum  J:339970 Mgi Id  MGI:7521851
Doi  10.1016/j.yjmcc.2023.08.004 Citation  Purdy AL, et al. (2023) Tnni3k influences cardiomyocyte S-phase activity and proliferation. J Mol Cell Cardiol 183:22-26
abstractText  Cardiomyocyte proliferation is a difficult phenomenon to capture and prove. Here we employ a retrospective analysis of single cell ventricular suspensions to definitively identify cardiomyocytes that have completed cell division. Through this analysis we determined that the capacity of cardiomyocytes to re-enter the cell cycle and complete cell division after injury are separate and variable traits. Further, we provide evidence that Tnni3k definitively influences both early and final stages of the cell cycle.
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