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Allele : Tg(Tbx6-cre/ERT2)1Pa transgene insertion 1, Virginia Papaioannou
Primary Identifier  MGI:6105951 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Tbx6-cre/ERT2)1Pa
Strain of Origin  C57BL/6 Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  Mouse BAC bmq-279H8 was modified to incorporate a cre/ERT2 with its own translational start site and polyA signal followed by an FRT-flanked kanamycin/neomycin cassette targeted to exon 1 of the Tbx6 gene. Flp-mediated recombination removed the FRT-flanked kan/neo cassette. Founder line 1Pa exhibited high levels of expression, and best recapitulated Tbx6 expression both temporally and spatially.
  • mutations:
  • Insertion
  • synonyms:
  • Tbx6-creERT2,
  • Tbx6-creERT2,
  • Tg(Tbx6-creERT2)<1Pa>,
  • Tg(Tbx6-creERT2)<1Pa>
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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Trail: Allele




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