| Primary Identifier | MGI:6118180 | Allele Type | Chemically induced (ENU) |
| Attribute String | Null/knockout | Gene | Slc25a46 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J x 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | ENU-mutagenesis induced a C to T transition, introducing a premature termination codon and resulting in a truncated protein of 95 amino acids instead of 418. This nonsense mutation presumably leads to a loss-of-function allele as the truncated protein would not contain the six conserved transmembrane regions. This mutant was identified in a screen for ataxia. |
