| Primary Identifier | MGI:6114782 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Myom2 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences ACCAGTTGTCCTATGACCAA, CATGAGAGACTGAAATACTT, TCTAATGCTTCACTAACCGT and CCTTTTCTACACCCCGAGGG, which resulted in a 508 bp deletion beginning at Chromosome 8 negative strand position 15,069,595 bp and ending after 15,069,088 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001260151 (exon 4) and 369 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 88 and early truncation 15 amino acids later. |
