| Primary Identifier | MGI:6143846 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Astl |
| Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The 13 amino acid cortical granule localizing motif was disrupted by the deletion of the sequences encoding the first 7 aa (52-DKDIPAI-58) encoded entirely by exon 2 with a protospacer adjacent motif (PAM) sequence. The resulting expressed protein lacked the amino acids 52-58. |