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Allele : Astl<em1Dean> astacin like metalloendopeptidase; endonuclease-mediated mutation 1, Jurrien Dean

Primary Identifier  MGI:6143846 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Astl
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The 13 amino acid cortical granule localizing motif was disrupted by the deletion of the sequences encoding the first 7 aa (52-DKDIPAI-58) encoded entirely by exon 2 with a protospacer adjacent motif (PAM) sequence. The resulting expressed protein lacked the amino acids 52-58.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Astl<delta>,
  • Astl<delta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele