| Primary Identifier | MGI:6114990 | Allele Type | Transgenic |
| Attribute String | Conditional ready, Inserted expressed sequence | Gene | Tg(CAG-cat,-ALOX15)1868Klv |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene consists of the CAG promoter consisting of a cytomegalovirus enhancer and a chicken beta-actin promoter, a loxP flanked chloramphenicol acetyl-transferase (cat) reporter gene with stop codons at the 3' end and human 15-lipoxygenase-1 cDNA. In the absence of Cre-recombination, the CAG promoter drives the expression of the cat reporter gene but not ALOX15. When Cre-mediated recombination removes the floxed cat reporter, CAG drives the expression of human ALOX15. Three lines were established: 1857, 1863, 1868. |
