Primary Identifier | MGI:6119463 | Allele Type | Targeted |
Attribute String | Conditional ready, Humanized sequence | Gene | Tubb5 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129P2/OlaHsd)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 4. A loxP, modified exon 4 with an E401K patient mutation and FRT-flanked neomycin resistance cassette were inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette. |