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Allele : Grn<tm1.2Pvd> granulin; targeted mutation 1.2, Philip Van Damme
Primary Identifier  MGI:6116381 Allele Type  Targeted
Attribute String  Null/knockout Gene  Grn
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked selection cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 8. Flp-mediated recombination removed the selection cassette and left exons 2 through 8 floxed. Cre-mediated recombination removed exons 2 through 8. ELISA confirmed the absence of protein expression in brain and spinal cords.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

3 Publication categories

Trail: Allele




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