| Primary Identifier | MGI:6147566 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ndrg4 |
| Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was introduced into intron 5 and a loxP site followed by a FRT-flanked PGK-neomycin resistance cassette were inserted into intron 7. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination deleted exons 5-7 in the germline. Western blot analysis confirmed absence of protein expression in the brain and heart. |
