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Allele : Brpf3<tm1b(EUCOMM)Wtsi> bromodomain and PHD finger containing, 3; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:6159126 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Brpf3
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_gt0 cassette was inserted at position 29035613 of Chromosome 17 upstream of exon 5 (Build GRCm39). The cassette is composed of an FRT site flanked lacZ reporter/neomycin resistance gene cassette followed by a loxP site. An additional loxP site is inserted downstream of exon 7 at position 29037893. Exons are thus flanked by loxP sites. Exons 5-7 were deleted through subsequent cre-mediated recombination, leaving a reporter-null allele. RT-PCR and immunoblotting experiments indicate that a truncated peptide is produced from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Brpf3<DELTA>,
  • Brpf3<DELTA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele