Primary Identifier | MGI:6147735 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Wwtr1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Cre-mediated excision of the parental Wwtr1tm1Hmc allele to generate global deletion of loxP flanked exon 2 of the Wwtr1 gene leaving a single loxP site and FRT-flanked neo cassette inserted in intron 2. CMV-cre transgnee was subsequently removed by crossing with wildtype mice. It is a null allele. |