| Primary Identifier | MGI:6147686 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(TCF/Lef1-lacZ)1Kudo |
| Strain of Origin | (C57BL/6 x C3H)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene contains the nlacZ (nuclear lacZ) gene under the control of a promoter consisting of six consensus lymphoid enhancer binding factor 1/transcription factor 3 (LEF/TCF)-binding motifs upstream of a minimal TK promoter, followed by a polyadenylation signal. The entire construct was flanked by two copies of insulator core elements to minimize positional effects imposed by chromosome structure. This construct is responsive to canonical Wnt/beta-catenin signal transduction. |
