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Allele : Cd3e<tm2.1Geno> CD3 antigen, epsilon polypeptide; targeted mutation 2.1, Genoway
Primary Identifier  MGI:6149565 Allele Type  Targeted
Gene  Cd3e Transmission  Germline
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  A C80G mutation was created and an FRT flanked neo cassette was inserted in intron 6 via homologous recombination. Flp mediated recombination removed the neo cassette. This mutation is located in the extracellular domain of the protein and is designed to prevent outside-in transmission of conformational changes in the TCR.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • C80G,
  • C80G
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele




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