| Primary Identifier | MGI:6149776 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Dyrk1a |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a single nucleotide insertion of a C at position 134 in exon 3 (c.134insC) resulting in a frameshift and truncation of the protein product. The five highest scoring predictive offtargets were located in either non-coding regions or intronic segments. |
