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Allele : Sorcs2<tm1.1Blhe> sortilin-related VPS10 domain containing receptor 2; targeted mutation 1.1, Barbara L Hempstead

Primary Identifier  MGI:6149994 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Sorcs2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The L1L2_Bact_P cassette was inserted at position 36386211 of Chromosome 5 upstream of the critical exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 2 at position 36386995. The critical exon 2 is thus flanked by loxP sites. Cre-mediated recombination without flp expression, produced a reporter knockout mouse.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele