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Allele : Eml4<em1(IMPC)J> echinoderm microtubule associated protein like 4; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6151437 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Eml4
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 2 guide sequences TTGTAAAACTCTGCTCCTTA and TCATCATGCACAGTTGTTCA, which resulted in a 216 bp deletion beginning at Chromosome 17 position 83,421,557 bp and ending after 83,421,772 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000484417 (exon 3) and 86 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 69 and early truncation 43 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele