| Primary Identifier | MGI:6154268 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Hmces |
| Strain of Origin | (C57BL/6 x 129)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Cas9 mRNA and single-guide RNA (sgRNA) targeting exon 2 was microinjected into the cytoplasm of zygote-stage embryos to induce deletions. Injected embryos were implanted in CD-1 foster mice and pups screened for deletions. Two lines were generated. This allele has a 388 bp deletion encompassing the translation initiation codon and catalytic invariant Cys2 codon. |
