Primary Identifier | MGI:6162240 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Shank3 |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | ES cells from Shank3tm1.1Bux mice were retargeted to carry a third loxP site downstream of exon 22. The allele contains a loxP site inserted upstream of exon 4, a second loxP site inserted downstream of exon 9, and a third loxP site downstream of exon 22. Cre-mediated recombination removed the exons 4-22. |