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Allele : Atp1a3<tm1Ute> ATPase, Na+/K+ transporting, alpha 3 polypeptide; targeted mutation 1, Ute Hochgeschwender

Primary Identifier  MGI:6162645 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atp1a3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation of G to A results in the amino acid substitution of asparigine for aspartic acid at position 801 (D801N). This mutation does not effect protein levels but reduces ATPase activity by 54-80%. An FRT-flanked neomycin resistance cassette was inserted.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Mashl<->,
  • Mashlool,
  • Mashlool,
  • Mashl<->,
  • D801N,
  • D801N
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele