Primary Identifier | MGI:6163502 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Atp1a3 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 17 was replaced with a floxed neomycin resistance cassette and a modified exon 17 in which nucleotide substitution (G to T) results in the amino acid substitution of tyrosine for aspartic acid (D801Y). Cre-mediated recombination removed the selection cassette. |