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Allele : Vtn<tm1.1Kekk> vitronectin; targeted mutation 1.1, Kevin K Kim

Primary Identifier  MGI:6155017 Allele Type  Targeted
Gene  Vtn Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 3 was replaced with one in which the RGD sequence was mutated to a nonintegrin-binding RGE sequence (CGGGGGGAC to CGGGGGGAG) and a FRT-flanked neomycin resistance cassette was inserted downstream of exon 6. Flp-mediated recombination removed the selection cassette. Western blot analysis confirmed expression of the mutated protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • VTN<RGE>,
  • VTN<RGE>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele