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Allele : Psmc5<tm1.1Itl> protease (prosome, macropain) 26S subunit, ATPase 5; targeted mutation 1.1, inGenious Targeting Laboratory
Primary Identifier  MGI:6155608 Allele Type  Targeted
Gene  Psmc5 Transmission  Germline
Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  An FRT-flanked neomycin resistance cassette was inserted upstream of exon 4. Exon 5 was modified with a nucleotide substitution (AGC to GAC) resulting in the amino acid substitution of aspartic acid for serine at position 120 (S120D). This modification creates a phospho-mimetic version. Flp-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Rpt6<S120D>,
  • Rpt6<S120D>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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