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Allele : Tagln2<em1(IMPC)Tcp> transgelin 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156457 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tagln2
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0973 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GAAGATCCAGGCCTCTTCGATGG, GCGCTATGGCATTAACACCACGG, CCTCGGAACTTCTCGGACAACCA, and GCATCTCAGGCCGGCATGACCGG targeting a critical region. This resulted in a inter-exon deletion of 909 bp Chr1:172505828 to 172506736; predicted to cause p.S84fs* (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele