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Allele : L2hgdh<em1(IMPC)Tcp> L-2-hydroxyglutarate dehydrogenase; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Primary Identifier  MGI:6156560 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  L2hgdh
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0908 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of ATCAGATACTTAAGTTCTGC and GGTCTATAAACATAAATATG targeting the 5' side and GGGAACCTGCTTATTTTGTC and GGAATAGCATAGTGCTCCTC targeting the 3' side of a critical region. This resulted in a 369-bp deletion from Chr12:69722029 to 69722397 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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