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Allele : Nphp3<tm1.1Nakaj> nephronophthisis 3 (adolescent); targeted mutation 1.1, Yoshiro Nakajima
Primary Identifier  MGI:6159873 Allele Type  Targeted
Attribute String  Altered localization Gene  Nphp3
Transmission  Germline Strain of Origin  C57BL/6NJcl
Is Recombinase  false Is Wild Type  false
molecularNote  A GGC -> GCC (G2A) mutation was inserted in exon 1 and a floxed neo cassette was inserted in intron 1 via homologous recombination. Cre mediated recombination removed the neo cassette. The mutation disrupts targeting of the protein to the cilia.
  • mutations:
  • Single point mutation
  • synonyms:
  • Nphp3<G2A>,
  • Nphp3<G2A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele




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