Primary Identifier | MGI:6160069 | Allele Type | Spontaneous |
Attribute String | Null/knockout | Gene | Myo6 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6Slc |
Is Recombinase | false | Is Wild Type | false |
molecularNote | RT-PCR and immunohistochemical analysis indicates greatly reduced mRNA expression and absence of protein expression in homozygous mice. However, no mutations in Myo6 exon sequence, exon-intron boundaries or promoter region are detected. An alternative splice variant of Myo6 is found in both rsv mice and wild-type mice. The non-recombinant region spans from D9Mit74 to D9Nok18. |