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Allele : Ces1g<tm1Reli> carboxylesterase 1G; targeted mutation 1, Richard Lehner

Primary Identifier  MGI:6164718 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ces1g
Transmission  Germline Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Part of exon 5 was replaced with a neomycin selection cassette. This resulted in the removal of the catalytic Ser221 in the encoded protein. Immunoblot analysis confirmed the absence of protein expression in the liver and small intestine of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ces1/Es-x<->,
  • Ces1/Es-x<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele