Primary Identifier | MGI:6160436 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Dlx2 |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6J)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites have been inserted into introns 1 and 3. A single FRT site in the 3' untranslated region (UTR), just 5' of the Pgk-neo cassette, marks the former site of a neomycin selection cassette that has been deleted by flp recombinase. Crossing mice bearing this allele with Cre recombinase-expressing mice will delete exons 2 and 3, which contain the entire homeodomain. |