|  Help  |  About  |  Contact Us

Allele : Ripk3<em2Kiwa> receptor-interacting serine-threonine kinase 3; endonuclease-mediated mutation 2, Kazuhiro Iwai

Primary Identifier  MGI:6187930 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ripk3
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A 5 bp deletion (TCCGC) was created in exon 3 using sgRNAs (targeting AACCCGAGTGCCCTCGGCCC and AGGTCCCGGTGCAGGAGCGG) with CRISPR/Cas9 technology, leading to a frameshift and premature stop codon (p.L75Afs*8). This mutation was created in oocytes containing the Rnf31tm1.1Kiwa allele. These two genes are tightly linked on chromosome 14.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • mRIP3-2,
  • mRIP3-2
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele