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Allele : Vcp<tm1.1Ccrs> valosin containing protein; targeted mutation 1.1, Christoph S Clemen and Rolf Schroder

Primary Identifier  MGI:6189547 Allele Type  Targeted
Attribute String  Null/knockout Gene  Vcp
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  In an attempt to introduce a mutation into exon 5, a floxed neo cassette was introduced into intron 4 then removed via Cre mediated recombination. The presence of the remaining loxP site resulted in aberrant splicing and subsequent nonsense-mediated decay of the mutant mRNA.
  • mutations:
  • Insertion
  • synonyms:
  • Vcp<tm1(ko)Cscl&Rfsr>,
  • Vcp<tm1(ko)Cscl&Rfsr>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele