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Allele : Vcp<tm2.1Ccrs> valosin containing protein; targeted mutation 2.1, Christoph S Clemen and Rolf Schroder
Primary Identifier  MGI:6189550 Allele Type  Targeted
Attribute String  Not Specified Gene  Vcp
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The triplet CGG in exon was replaced by a TGT resulting in the replacement of an arginine with a cysteine at position 155 (R155C) and a floxed neo cassette was inserted in intron 4. Cre mediated recombination removed the neo cassette. The remaining loxP site is located further upstream than in mice carrying Vcp tm1.1Ccrs to avoid the splicing issue present in this allele.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Vcp<tm2(R155C)Ccrs>,
  • Vcp<tm2(R155C)Ccrs>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

6 Publication categories

Trail: Allele




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