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Allele : Tg(Myh6-Prkaca)33Eno transgene insertion 33, Eric N Olson
Primary Identifier  MGI:6193912 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-Prkaca)33Eno
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The alpha-MHC promoter drives the expression of the PKA-Calpha cDNA. Overexpression of the catalytic subunit results in constitutive activation of the enzyme without a requirement for cAMP. Assays for activity in heart extracts show that Prkaca activity is elevated 2.4-fold in line 33.
  • mutations:
  • Insertion
  • synonyms:
  • alphaMHC-PKA Tg33,
  • alphaMHC-PKA Tg33
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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