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Allele : Ptprc<M6Btlr> protein tyrosine phosphatase receptor type C; mutation 6, Bruce Beutler

Primary Identifier  MGI:6200077 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Ptprc
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to G transversion at base pair 138,067,890 (v38) on chromosome 1, or base pair 107,867 in the GenBank genomic region NC_000067 encoding Ptprc. The mutation corresponds to residue 3,508 in the mRNA sequence NM_001111316 within exon 31 of 33 total exons. The mutation results in a cysteine to glycine substitution at position 1,157 (C1157G) in variant 1 of the CD45 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Dumpling,
  • Dumpling
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele