| Primary Identifier | MGI:6202420 | Allele Type | Targeted |
| Attribute String | Conditional ready, Reporter | Gene | Gt(ROSA)26Sor |
| Transmission | Germline | Strain of Origin | C57BL/6JJic |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = Wit 9 (C57BL/6JJic). |
| molecularNote | A construct containing the CAG promoter with a SloxM1-STOP-SloxM1 cassette preceding tdTomato sequence was inserted into the intron of the Gt(ROSA)26Sor locus via homologous recombination in Wit 9 ES cells. SCre-mediated recombination of this allele results in the expression of the tdTomato reporter driven by the CAG promoter. SCre/SloxP is a site-specific recombination system that was derived from plasmid 1 of Shewanella sp. ANA-3. SCre is a recombinase that recognizes its own specific target sites (SloxP). |
