Primary Identifier | MGI:6202431 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | C57BL/6JJic |
Is Recombinase | true | Is Wild Type | false |
description | ES cell line = Wit 9 (C57BL/6JJic). |
molecularNote | A construct containing the Scre gene driven by the CAG promoter was inserted into the intron of the Gt(ROSA)26Sor locus via homologous recombination in Wit 9 ES cells. SCre/SloxP is a site-specific recombination system that was derived from plasmid 1 of Shewanella sp. ANA-3. SCre is a recombinase that recognizes its own specific target sites (SloxP). |