Primary Identifier | MGI:6202045 | Allele Type | Endonuclease-mediated |
Attribute String | Inducible, Recombinase | Gene | Alb |
Strain of Origin | Not Specified | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The line was generated by inserting a cDNA encoding IRES-Dre recombinase fused with a mutant form of estrogen receptor hormon-binding domaine C (ERT2) into in-frame with the translational termination codon of the last coding exon of Alb by homologous recombination using the CRISPR/Cas9 technology. This knock-in strategy leads to simultaneous expression of DreER and endogenous albumin. |