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Allele : Klf5<M1Btlr> Kruppel-like transcription factor 5; mutation 1, Bruce Beutler

Primary Identifier  MGI:6200268 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Klf5
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced C to T transition at base pair 99,302,230 (v38) on chromosome 14, or base pair 3,540 in the GenBank genomic region NC_000080 encoding Klf5. The mutation corresponds to residue 1,382 in the mRNA sequence NM_009769 within exon 2 of 4 total exons. The mutation results in an arginine (R) to cysteine (C) substitution at position 360 (R360C) in the KLF5 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Bernie,
  • Bernie
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele