| Primary Identifier | MGI:6200285 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Stk4 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| molecularNote | ENU-induced T to C transition at base pair 164,099,827 (v38) on chromosome 2, or base pair 25,715 in the GenBank genomic region NC_000068 within the donor splice site of intron 8. The effect of the mutation at the cDNA and protein level have not examined, but the mutation is predicted to result in the use of cryptic splice site within intron 8. The resulting transcript would have a 62-base pair insertion of intron 8, which would cause a frame shifted protein beginning after amino acid 319 of the protein. The protein would terminate after the inclusion of 43 aberrant amino acids. |
