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Allele : Gt(ROSA)26Sor<tm1(DDIT3)Myz> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Makoto Miyazaki
Primary Identifier  MGI:6202519 Allele Type  Targeted
Attribute String  Conditional ready, Epitope tag, Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6J x 129X1/SvJ)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector is designed with a loxP-flanked transcriptional STOP cassette (PGK-puro-SV40 polyA), and an HA-tagged human DNA-damage inducible transcript 3 (DDIT3)-WPRE-BGH-pA cassette. This vector was inserted into the Gt(ROSA)26Sor locus via a FLP recombinase-mediated cassette exchange method. Specifically, the R26FNF3-1F1 (1F1) ES cell line used to generate the mutation was created by targeting Gt(ROSA)26Sor with a FRT- and F3-flanked PGK-neomycin selection cassette by homologous recombination in EC7.1 ES cells.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26-CHOP<loxtg>,
  • Rosa26-CHOP<loxtg>
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1 Feature

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Genome

1 Expresses

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0 Mutation Involves

Phenotype

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