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Allele : Wnt4<em1Amc> wingless-type MMTV integration site family, member 4; endonuclease-mediated mutation 1, Andrew P McMahon
Primary Identifier  MGI:6197855 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Wnt4
Strain of Origin  (C57BL/6 x SJL/J)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 endonuclease mediated genome editing is used to delete the distal enhancer element (Chr4:137216986-137217756). Expression of Wnt4 is reduced in the renal vesicles of the kidneys, but not in the renal medulla as determined by in situ hybridization.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Wnt4-deltaDE,
  • Wnt4-DE,
  • Wnt4-DE,
  • Wnt4-deltaDE
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Phenotype

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