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Allele : Tg(GFAP-ATXN7*92Q)2521Als transgene insertion 2521, Albert La Spada
Primary Identifier  MGI:6194621 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(GFAP-ATXN7*92Q)2521Als
Strain of Origin  (C57BL/6J x C3H/HeJ)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A 2.2-kb human glial fibrillary acidic protein fragment of the promotor region drives the expression of a flag and c-myc tagged human ataxin-7 cDNA bearing 92 glutamines. Western blot analysis confirmed expression of the transgene. Immunostaining confirmed that expression is restricted to regions of the cerebellum in which Bergmann glia reside and is probably nuclear and cytosolic. This is the moderate expressing line.
  • mutations:
  • Insertion
  • synonyms:
  • Gfa2-SCA7-92Q line 2,521,
  • Gfa2-SCA7-92Q line 2,521
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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