| Primary Identifier | MGI:6195300 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Atp7a |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTAGGCATTGGAATGTGAAA and GTTTAGCAGGAAAGGCACTG, which resulted in a 951 bp deletion beginning at Chromosome X position 106,084,876 bp and ending after 106,085,826 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000378424 (exon 3) and 461 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 40 and early truncation 2 amino acids later. |
