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Allele : Hoxd3<em1Ddu> homeobox D3; endonuclease-mediated mutation 1, Denis Duboule

Primary Identifier  MGI:6195703 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Hoxd3
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A 67 bp deletion was created using sgRNAs 5'-GTACGCCGTGCGCACCCTCT-3' and 5'-GGCGCGGCCGGCACAGATAG-3' and CRISPR/Cas9 technology. This deletion in the second exon crates a frameshift and premature stop codon. As a result virtually the entire homeodomain is eliminated.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Hoxd3<hd>,
  • Hoxd3<hd>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele